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Research Papers

2009

  • Noguchi A. Amino Acids and Peptides: Building Blocks for Skin Proteins. Nutritional Cosmetics: Beauty from within. 2009;287-317.
  • Tsuneyoshi Y, Sato M, Tomonaga S, Yamane H, Morishita K, Denbow DM, Furuse M. Oral administration of Excitin-1(β-alanyl-L-leucine)alters behavior and brain monoamine and amino acid concentrations in rats. Nutritional　Neuroscience. 2009;12:175-182.
  • Sakakibara H, Miyashita T, Matsui A, Osaki A, Suzuki A, Ikeda T, Morishita K, Shimoi K. Effects of St John's Wort extracts on corticosterone levels dysregulated by social isolation stress. Journal of Traditional Medicines. 2009;26:86-92.
  • Koitaya N, Ezaki J, Nishimuta M, Yamauchi J, Hashizume E, Morishita K, Miyachi M, Sasaki S, Ishimi Y. Effect of Low Dose Vitamin K2(MK-4) supplementation on Bio-Indices in Postmenopausal Japanese Women. J Nutr Sci Vitaminol. 2009;55:15-21.
  • Ikeda M, Mitsuhashi S, Tanaka K, Hayashi M. Reengineering of a Corynebacterium glutamicum L-arginine and L-citrulline producer. Appl Environ Microbiol. 2009 Mar;75(6):1635-41. Epub 2009 Jan 9.

2008

  • Tsuneyoshi Y, Tomonaga S, Yaname H, Morishita K, Denbow DM, Furuse M. Central Administration of L-Ser-L-His and L-Ile-L-His Induced Sedative Effects Under an Acute Stressful Condition in Chicks. Letters in Drug Design & Discovery. 2008;5:65-68.
  • Tsuneyoshi Y, Yamane H, Tomonaga S, Morishita K, Denbow DM, Furuse M. Reverse structure of carnosine-induced sedative and hypnotic effects in the chick under acute stress. Life Science. 2008;82:1065-1069.
  • Sugino T, Shirai T, Kajimoto Y, Kajimoto O. L-Ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism. Nutrition Research. 2008; 28:738-743.
  • Ohnishi J, Mizoguchi H, Takeno S, Ikeda M. Characterization of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain. Mutat Res. 2008 Jan 8;649(1-2):239-44. Epub 2007 Oct 18.

2007

  • Tabata K, Hashimoto S. Fermentative production of L-alanyl-L-glutamine by a metabolically engineered Escherichia coli strain expressing L-amino acid alpha-ligase. Appl Environ Microbiol. 2007 Oct;73(20):6378-85. Epub 2007 Aug 24.

2006

  • Hayashi M, Ohnishi J, Mitsuhashi S, Yonetani Y, Hashimoto S, Ikeda M. Transcriptome analysis reveals global expression changes in an industrial L-lysine producer of Corynebacterium glutamicum. Biosci Biotechnol Biochem. 2006 Feb;70(2):546-50.
  • Ohnishi J, Ikeda M. Comparisons of potentials for L-lysine production among different Corynebacterium glutamicum strains. Biosci Biotechnol Biochem. 2006 Apr;70(4):1017-20.
  • Ikeda M, Ohnishi J, Hayashi M, Mitsuhashi S. A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production. J Ind Microbiol Biotechnol. 2006 Jul;33(7):610-5.
  • Hayashi M, Mizoguchi H, Ohnishi J, Mitsuhashi S, Yonetani Y, Hashimoto S, Ikeda M. A leuC mutation leading to increased L-lysine production and rel-independent global expression changes in Corynebacterium glutamicum.　Appl Microbiol Biotechnol. 2006 Oct;72(4):783-9. Epub 2006 Aug 30.
  • Mitsuhashi S, Hayashi M, Ohnishi J, Ikeda M. Disruption of malate:quinone oxidoreductase increases L-lysine production by Corynebacterium glutamicum. Biosci Biotechnol Biochem. 2006 Nov;70(11):2803-6. Epub 2006 Nov 7.
  • Tokuyama E, Shibasaki T, Kawabe H, Mukai J, Okada S, Uchida T. Bitterness suppression of BCAA solutions by L-ornithine. Chem. Pharm. Bull. (Tokyo) 2006;54(9):1288-1292.

2005

  • Tabata K, Ikeda H, Hashimoto S. ywfE in Bacillus subtilis codes for a novel enzyme, L-amino acid ligase. J Bacteriol 2005;187:5195-5202.
  • Ohnishi J, Katahira R, Mitsuhashi S, Kakita S, Ikeda M.　A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum. FEMS Microbiol Lett. 2005 Jan 15;242(2):265-74.
  • Tabata K, Ikeda H, Hashimoto S. ywfE in Bacillus subtilis codes for a novel enzyme, L-amino acid ligase. J Bacteriol. 2005 Aug;187(15):5195-202.
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